Research: Protective effect apparent during first year of life —

“We interviewed 128 mothers of infants multiple times over a period of 18 months and asked how they cleaned their child’s pacifier,” says allergist Eliane Abou-Jaoude, MD, ACAAI member and lead author on the study conducted by Henry Ford Health System in Detroit. “We found the children of mothers who sucked on the pacifier had lower IgE levels.” IgE is a type of antibody related to allergic responses in the body. Although there are exceptions, higher IgE levels indicate a higher risk of having allergies and allergic asthma.”

Of the 128 mothers completing multiple interviews, 58 percent reported current pacifier use by their child. Of those who had a child using a pacifier, 41 percent reported cleaning by sterilization, 72 percent reported hand washing the pacifier, and 12 percent reported parental pacifier sucking.

“We found that parental pacifier sucking was linked to suppressed IgE levels beginning around 10 months, and continued through 18 months,” says allergist Edward Zoratti, MD, ACAAI member and co-author of the study. “Further research is needed, but we believe the effect may be due to the transfer of health-promoting microbes from the parent’s mouth. It is unclear whether the lower IgE production seen among these children continues into later years.”

“We know that exposure to certain microorganisms early in life stimulates development of the immune system and may protect against allergic diseases later,” says Dr. Abou-Jaoude. “Parental pacifier sucking may be an example of a way parents may transfer healthy microorganisms to their young children. Our study indicates an association between parents who suck on their child’s pacifier and children with lower IgE levels but does not necessarily mean that pacifier sucking causes lower IgE.”

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Materials provided by American College of Allergy, Asthma, and Immunology. Note: Content may be edited for style and length.